This article discusses the strategic importance of the Strait of Hormuz as a vital artery of the global economy and highlights the ongoing conflict between Iran and the United States over control of the waterway, illustrating the use of economic coercion. It emphasizes that economic weaponization can disrupt global economic interdependence and ultimately harm the user, drawing on historical examples. Furthermore, it suggests a shift in global economic priorities with national security and resilience taking precedence, and that economic weaponization is likely to continue.